CBD and the opioid epidemic: The potential of CBD as an alternative to opioids for pain management and addiction treatment.


The opioid epidemic is a global crisis affecting millions of people. Opiates, such as heroin and prescription pain relievers, are highly addictive and can cause serious health problems, including overdose and death. Despite the severity of this crisis, opioids remain an important part of healthcare pain management.

The Potential of CBD: An Emerging Alternative

Cannabidiol, more commonly known as CBD, is increasingly recognized as a potential alternative to opioids. CBD, a non-psychoactive component of cannabis, has been shown to relieve pain and help treat opioid addiction. But how exactly does it work, and how does it compare to opioids? Let's take a closer look at that.

CBD and the opioid epidemic: The potential of CBD as an alternative to opioids for pain management and addiction treatment.

Understanding of Opioids and CBD

What are Opioids? Their Uses and Risks

Opioids are a class of medications known for their powerful pain-relieving properties. They are often prescribed to treat moderate to severe pain, which cannot be controlled by other pain relievers such as acetaminophen or ibuprofen. These drugs work by binding to opioid receptors in the body, particularly in the brain and spinal cord, reducing the sensation of pain.

Opioids include drugs such as morphine, codeine, fentanyl, and oxycodone, as well as illegal drugs such as heroin. While effective in reducing pain, opioids also carry a high risk of abuse and dependence. Prolonged use can lead to physical tolerance, meaning higher doses are needed to achieve the same effect. This can eventually lead to a condition known as opioid use disorder, a serious form of addiction that can have serious health and social consequences.

According to a study published in the American Journal of Psychiatry , opioid abuse is a growing problem worldwide, with an estimated 26.4 million to 36 million people abusing opioids worldwide. This underlines the importance of finding safer alternatives for pain management.

What is CBD? Its Use and Potential Benefits

Cannabidiol, more commonly known as CBD, is a naturally occurring compound in the cannabis plant. It is one of more than a hundred cannabinoids in the plant, but unlike the best-known cannabinoid, tetrahydrocannabinol (THC), CBD is non-psychoactive. This means that it does not cause the "high" or euphoria often associated with cannabis.

CBD has a wide range of potential health benefits. It has been shown to be effective in reducing pain, inflammation and anxiety, and may also help manage symptoms of epilepsy and other neurological conditions. In addition, there is growing evidence that CBD has potential as a treatment for opioid addiction.

A study published in the American Journal of Psychiatry showed that CBD can be effective in reducing cravings and anxiety in people with heroin addiction. The study suggests that CBD may help reduce the cravings that often lead to relapse in patients recovering from opioid addiction, making it a potentially useful tool in addiction treatment.

In addition, CBD has also been shown to be effective in reducing chronic pain. According to a review published in The Journal of Experimental Medicine , cannabinoids like CBD can reduce inflammation and relieve neuropathic pain, a type of chronic pain that is difficult to treat with traditional medicine.

CBD is available in several forms, including oils, tinctures, edibles, and topicals. It can also be inhaled through vaping. In addition, different flavors are available, such as Watermelon , Berry Gelato , and Bubble Gum , which can make it a more pleasant experience for patients.

It's important to note that while CBD shows promise, a lot of research is still needed to fully understand how it works and how best to use it for pain management and addiction treatment. In addition, while CBD is generally well tolerated, it can cause side effects in some people, such as dry mouth, fatigue, and changes in appetite and weight. That's why it's important to talk to a health care professional before you start using CBD.

In conclusion, both opioids and CBD play an important role in pain management. However, given the risks associated with opioids, including abuse and dependence, there is an urgent need for safer alternatives. CBD, with its pain-relieving properties and potential as a treatment for opioid addiction, offers a promising alternative. While there is still much to learn about CBD, it is clear that it can play an important role in the future of pain management and addiction treatment.

CBD vs Opioids for Pain Management

The Role of Opioids in Pain Management

Opioids have long been a standard treatment for severe pain. They are often prescribed for conditions such as cancer, postoperative pain, and chronic conditions that cause severe pain. Opioids work by binding to opioid receptors in the body, reducing the sensation of pain. This makes them particularly effective in managing severe and persistent pain.

However, the use of opioids carries significant risks. They are highly addictive and can lead to physical dependence and tolerance. This means that over time, patients may need higher doses to achieve the same level of pain relief, which increases the risk of overdose. In addition, opioids can have serious side effects, including drowsiness, nausea, constipation, and difficulty breathing. In severe cases, an opioid overdose can lead to respiratory failure and death.

According to the World Health Organization , more than 500 people worldwide die of opioid overdose every day. This underlines the importance of finding safer alternatives for pain management.

The Role of CBD in Pain Management

Cannabidiol, more commonly known as CBD, has been shown to be effective in reducing various types of pain, including chronic pain, neuropathic pain, and pain associated with conditions such as fibromyalgia and multiple sclerosis.

CBD works by interacting with the body's endocannabinoid system, a complex system involved in regulating various bodily functions, including pain. Unlike opioids, which work by blocking the pain receptors in the body, CBD appears to work by changing the way the body perceives pain.

One of the main benefits of CBD is that it does not carry the same risk of addiction and overdose as opioids. This makes it an attractive alternative for patients looking for a safer pain management option.

In addition, different flavors are available, such as Watermelon , Berry Gelato , and Bubble Gum , which can make it a more pleasant experience for patients. These flavors can help mask the bitter taste of CBD oil, making it easier for patients to take their medication.

It's important to note that while CBD shows promise, a lot of research is still needed to fully understand how it works and how best to use it for pain management. In addition, while CBD is generally well tolerated, it can cause side effects in some people, such as dry mouth, fatigue, and changes in appetite and weight. That's why it's important to talk to a health care professional before you start using CBD.

Comparative Analysis: Efficacy, Side Effects and Risks

While opioids are effective at reducing severe pain, they carry significant risks, including dependence and overdose. In addition, they can have serious side effects, including drowsiness, nausea, constipation, and difficulty breathing.

On the other hand, CBD has shown to be effective in reducing pain without these risks. Unlike opioids, which can cause physical dependence and tolerance, CBD is not addictive and has no known overdose risks. In addition, CBD has fewer side effects than opioids. The most common side effects of CBD are generally mild and can include dry mouth, fatigue, and changes in appetite and weight.

A study published in the European Journal of Pain showed that CBD can be effective in reducing chronic pain. The study found that patients taking CBD reported a significant reduction in pain compared to those taking a placebo.

Another study published in Addiction Biology found that CBD may help reduce opioid cravings and reduce anxiety, which may help prevent relapse in people recovering from opioid addiction.

In conclusion, both opioids and CBD play an important role in pain management. However, given the risks associated with opioids, including abuse and dependence, there is an urgent need for safer alternatives. CBD, with its pain-relieving properties and potential as a treatment for opioid addiction, offers a promising alternative. While there is still much to learn about CBD, it is clear that it can play an important role in the future of pain management and addiction treatment.

It is important to emphasize that while CBD shows promise, it is not a panacea. It is just one tool in a comprehensive approach to pain management and addiction treatment. It's also important to remember that everyone is different and what works for one person may not work for another. That's why it's important to talk to a healthcare provider before starting CBD or any other new treatment.

In the future, we will likely see more research on CBD and its potential as an alternative to opioids. This research will help us better understand how CBD works, how best to use it and for whom it can be most effective. Meanwhile, CBD remains a promising option for people seeking a safer alternative to opioids for pain management and addiction treatment.

CBD and Opioid Addiction Treatment

Opioid Use Disorder: An Overview

Opioid use disorder is a serious condition characterized by the inability to control opioid use despite negative consequences. It is a form of addiction that can develop after using opioids, both prescribed and illegal. This disorder can lead to serious health problems, including overdose and death, and can also have significant social and economic consequences.

According to the American Psychiatric Association , opioid use disorder includes a range of symptoms, including a strong urge to use opioids, inability to control use, continued use despite negative consequences, and withdrawal symptoms upon discontinuation. It is a chronic condition that often requires long-term treatment and ongoing monitoring.

CBD in Addiction Treatment: Current Research Findings

Recent research suggests that CBD may help treat opioid addiction. A study published in the American Journal of Psychiatry found that CBD may be effective in reducing opioid cravings and anxiety, two major factors contributing to relapse in people recovering from opioid addiction.

CBD works by interacting with the body's endocannabinoid system, a complex system involved in regulating several bodily functions, including pain, mood, and reward. By modulating the endocannabinoid system, CBD may help reduce opioid cravings and relieve the symptoms of withdrawal.

In addition, CBD may help reduce the symptoms of opioid withdrawal, including anxiety, insomnia, pain, and nausea. A study published in Neuropsychopharmacology found that CBD may be effective in reducing the severity of withdrawal symptoms in rats chronically exposed to morphine.

Case Studies: CBD Use in Opioid Addiction Recovery

There are several case studies illustrating the potential of CBD in the treatment of opioid addiction. One of these studies, published in The Permanente Journal , describes the case of a 10-year-old boy who was successfully treated with CBD for his opioid addiction. The boy, who previously relied on opioids for pain management after surgery, was able to reduce and eventually stop his opioid use with the help of CBD.

Another case study, published in The Journal of Pain and Symptom Management , describes the case of a woman who suffered from severe opioid addiction due to chronic pain. The woman was able to reduce her opioid use and manage her pain with the help of CBD.

These case studies show that CBD can help reduce drug craving and drug-related behaviors, and contribute to successful recovery. They also underline the importance of further research into the role of CBD in the treatment of opioid addiction.

It is important to note that while these case studies are promising, they are based on individual cases and not large-scale clinical trials. Therefore, more research is needed to fully understand the effectiveness of CBD in the treatment of opioid addiction.

In conclusion, opioid use disorder is a serious and growing health problem. While opioids are effective in managing severe pain, they carry significant risks, including dependence and overdose. CBD, on the other hand, offers a promising alternative to opioids for pain management and addiction treatment. While there is still much to learn about CBD and its potential in the treatment of opioid addiction, current research findings and case studies suggest that it may be a valuable tool in the fight against the opioid epidemic.

The Science Behind CBD And Opioids

The Biological Mechanisms of Opioids

Opioids are powerful pain relievers that work by binding to opioid receptors in the body. These receptors are part of the opioid system, which plays a critical role in the regulation of pain, reward and addictive behavior. When opioids bind to these receptors, they reduce the perception of pain and induce a feeling of euphoria.

However, long-term use of opioids can lead to physical dependence and tolerance. This means that the body adapts to the presence of the drug, requiring higher doses to achieve the same effect. This can lead to a cycle of increasing use, which increases the risk of overdose and other serious health problems.

In addition, opioids can also decrease the body's production of natural opioids, such as endorphins. This can lead to an increased sensitivity to pain, making it more difficult to manage pain without the use of opioids.

The Biological Mechanisms of CBD

Cannabidiol, more commonly known as CBD, is one of many cannabinoids found in the cannabis plant. Unlike THC, the psychoactive component of cannabis, CBD is non-psychoactive, meaning it doesn't cause a "high."

CBD works by interacting with the endocannabinoid system in the body. Consisting of a network of cannabinoid receptors and endocannabinoids, this system plays a role in a wide variety of bodily functions, including pain, mood, sleep, and immune response.

CBD can help reduce pain by modulating the activity of this system. It can do this by inhibiting the absorption of endocannabinoids, increasing their levels in the body, or by binding to non-cannabinoid receptors involved in pain regulation.

Interactions Between CBD and Opioids

There is some evidence that CBD and opioids may work synergistically to reduce pain. A study published in The European Journal of Pain showed that the combination of CBD and opioids led to greater pain relief than using either alone.

This suggests that CBD has the potential to enhance the effectiveness of opioids, requiring lower doses of opioids to achieve the same level of pain relief. This can help reduce the risk of dependence and overdose, which is an important benefit given the current opioid epidemic.

However, it is important to note that more research is needed to fully understand this interaction and to determine how best to use CBD in conjunction with opioids for pain management.

Legal and Regulatory Aspects

The Legal Status of Opioids: A Global Perspective

Opioids are legal by prescription in many countries, but their use is highly regulated due to their high risk of abuse and dependence. In the United States, for example, opioids are classified as Schedule II drugs, meaning they have a high potential for abuse and abuse can lead to severe psychological or physical dependence.

However, in some countries, such as Russia and China, opioids are illegal regardless of prescription. This means that the possession, production and distribution of opioids are punishable by severe penalties.

The Legal Status of CBD: Current Laws and Regulations

The legal status of CBD varies worldwide. In some countries, such as Canada and Uruguay, it is completely legal. In other countries, such as the United States, it is legal at the federal level, but the laws vary from state to state.

In the Netherlands, CBD is legal as long as the THC content is below 0.05%. This means that CBD products, such as oils, tinctures, and edibles, can be legally purchased and consumed as long as they meet this THC limit.

It is important to note that while CBD is legal in many countries, it is still subject to regulation. In many cases, CBD products must meet strict quality and safety standards, and can only be sold through licensed retailers.

Regulatory Challenges and Considerations: FDA and Beyond

While CBD shows promise as an alternative to opioids, there are still many regulatory challenges and considerations. The US Food and Drug Administration (FDA), for example, has not yet issued formal guidelines for the use of CBD for medical purposes.

This means that while CBD may be legal, it is still not approved as a medical treatment in many jurisdictions. This can make it difficult for patients and healthcare providers to access reliable information about CBD and how it can be used for pain management and addiction treatment.

In addition, there are also challenges in terms of quality control and product labeling. Since the CBD market is still relatively new, there are concerns about the consistency and purity of CBD products. In some cases, products sold as CBD may contain other ingredients or may not contain the amount of CBD stated on the label.

Despite these challenges, regulatory agencies such as the FDA are working on guidelines for the safe and effective use of CBD. In the meantime, it's important for consumers to do their due diligence and only buy CBD products from reputable sources.

In conclusion, both CBD and opioids have important roles to play in pain management and addiction treatment. However, given the risks associated with opioids, including dependence and overdose, there is an urgent need for safer alternatives. CBD, with its pain-relieving properties and potential as a treatment for opioid addiction, offers a promising alternative. While there is still much to learn about CBD, it is clear that it can play an important role in the future of pain management and addiction treatment.

Public Perception and Patient Experiences

Public Perception of Opioids: The Stigma and Misconceptions

Despite their effectiveness in pain management, opioids are often viewed negatively due to their high risk of abuse and dependence. This stigma can lead to misconceptions and misunderstandings about opioids, which may make people who need them for pain management hesitant to use them.

One of the most common misconceptions is that anyone who takes opioids will become addicted. While it is true that opioids carry a high risk of addiction, it is also true that they are safe to use under medical supervision. It is important that patients and the public understand that opioids can be a valuable tool in pain management when used correctly.

There is an urgent need for better education and awareness about the proper use of opioids. This includes understanding the risks of opioids, recognizing the signs of abuse and dependence, and knowing the resources available to those struggling with opioid addiction.

Public Perception of CBD: Changing Attitudes

The public perception of CBD has changed significantly in recent years. Once seen as a controversial substance due to its association with cannabis, CBD is now increasingly recognized for its potential health benefits.

More and more people see CBD as a safe and effective alternative to traditional medicines. This is due in part to the growing body of scientific research supporting the benefits of CBD, as well as personal testimonials from people who have used CBD for conditions such as chronic pain, anxiety, and insomnia.

It is also important to note that the public perception of CBD is affected by changing laws and regulations. In many countries, including the Netherlands, CBD is legal and easily accessible, contributing to its growing acceptance and popularity.

Patient Experiences: Personal Stories and Anecdotes

There are countless personal stories and anecdotes from people who have used CBD for pain management and addiction treatment. These stories, while anecdotal, provide valuable insights into the potential benefits of CBD.

For example, some people report that CBD has helped them reduce or stop their use of opioids. Others say CBD has helped them manage their pain where other treatments have failed. These stories highlight the potential of CBD as an effective alternative to opioids.

However, it is important to note that while these stories are inspiring, they should not be taken as definitive proof of CBD's effectiveness. Everyone is different and what works for one may not work for another. That's why it's important to talk to a healthcare provider before starting CBD or any other treatment.

The Role of Healthcare Professionals: Education and Advocacy

Healthcare providers play a critical role in educating patients about the risks and benefits of both opioids and CBD. By providing patients with accurate and up-to-date information, healthcare providers can help promote the safe and effective use of these medications.

Healthcare providers can also advocate for greater access to CBD and other non-opioid treatments for pain management. This may include advocating for regulatory changes, promoting research into CBD and other non-opioid treatments, and supporting patients who choose to use CBD.

The Missing Link: Non-Opioid Treatments for Chronic Pain

High-Tech Methods and Complementary Therapies

In addition to CBD, there are several other non-opioid treatments for chronic pain, including high-tech methods such as neuromodulation and complementary therapies such as acupuncture and physical therapy.

Neuromodulation, for example, includes techniques such as spinal cord stimulation and peripheral nerve stimulation, which use electrical signals to change the way the body perceives pain. These techniques can be particularly effective for people with severe chronic pain who do not respond to other treatments.

Complementary therapies such as acupuncture and physical therapy can also play an important role in pain management. These therapies can help reduce pain, improve mobility, and improve overall quality of life.

The Role of CBD in Non-Opioid Treatments

CBD may play an important role in non-opioid treatments for chronic pain. It can be used as a standalone treatment or in combination with other therapies to reduce pain and improve quality of life.

In addition, our effects blends enriched with terpenes, such as our sleep and recovery blends , can contribute to better sleep quality and faster recovery. These blends contain carefully selected terpenes designed to promote specific effects, making them a valuable addition to your pain management and recovery strategy.

Patient Experiences and Case Studies

There are numerous patient experiences and case studies illustrating the effectiveness of CBD in non-opioid treatments for chronic pain. These stories provide valuable insights into how CBD can be used to manage pain and improve quality of life.

For example, a study published in the European Journal of Pain found that CBD was effective in reducing pain and improving sleep quality in patients with chronic pain. In this study, patients reported significant improvements in their pain and sleep quality after using CBD.

Another study, published in The Journal of Pain , found that CBD was effective at reducing pain in patients with fibromyalgia. In this study, patients reported a significant reduction in their pain intensity after using CBD.

These and other studies highlight the potential of CBD as a safe and effective alternative to opioids in the treatment of chronic pain. While more research is needed, these findings suggest that CBD could be a valuable addition to the pain management toolkit.

Future Research and Developments

Current Gaps in Research: What We Don't Know Yet

While there is some promising research on CBD and opioids, there are still many unanswered questions. One of the biggest challenges in CBD and opioid research is the lack of large-scale, long-term studies. Many of the current studies are small-scale, short-term, or preclinical, meaning they've been done on animals rather than humans.

For example, we still don't know exactly how CBD works to reduce pain and treat opioid addiction. While we know that CBD interacts with the endocannabinoid system in the body, the precise mechanism of this interaction is not yet fully understood.

In addition, there is still much to learn about the optimal dosage of CBD for various conditions, the possible interactions between CBD and other drugs, and the long-term effects of CBD use.

Potential Future Developments in CBD and Opioid Research

Despite these challenges, there are many exciting possible future developments in CBD and opioid research. For example, researchers are currently exploring the possibility of using synthetic THC and other cannabinoids in combination with CBD for pain management and addiction treatment.

Synthetic THC, also known as dronabinol, is already approved by the FDA for the treatment of nausea and vomiting caused by chemotherapy, as well as for the treatment of weight loss and anorexia in people with HIV/AIDS. The potential of synthetic THC and other cannabinoids to work in tandem with CBD to reduce pain and treat opioid addiction is an exciting area of ​​future research.

In addition, there are ongoing studies into the potential benefits of CBD for other conditions, including anxiety, depression, sleep disorders, epilepsy, and even cancer. These studies can help us better understand the full scope of CBD's potential uses.

The Future of Pain Management and Addiction Treatment: A Prediction

Given current trends and research findings, it is likely that CBD will play an increasingly important role in pain management and addiction treatment in the future. CBD's potential to treat opioid addiction and reduce pain without the risk of abuse and dependence makes it a promising alternative to opioids.

Conclusion

Summary of Findings: What We Learned

We have learned that CBD is a promising alternative to opioids for pain management and addiction treatment. It has been shown to be effective in reducing pain and treating opioid addiction, without the risk of abuse and dependence associated with opioids.

In addition, we also learned about the complexity of the opioid epidemic and the challenges associated with managing it. While opioids are effective in managing severe pain, they carry significant risks, including dependence, overdose, and death. This makes finding safe and effective alternatives to opioids, such as CBD, all the more important.

Implications for the Opioid Epidemic: A New Hope?

Given the current opioid epidemic, CBD offers a new hope. CBD's potential to reduce pain and treat opioid addiction may play an important role in combating this crisis.

However, it is important to note that CBD is not a panacea. While promising, it is only one tool in the pain management and addiction treatment toolkit. It is also essential that we continue to invest in research, education and policy changes to tackle the opioid epidemic.

Final Thoughts and Future Directions: Where Do We Go From Here?

While there is still much to learn about CBD and opioids, it is clear that CBD can play an important role in the future of pain management and addiction treatment. It is our hope that this article has contributed to your understanding of "CBD and the opioid epidemic" and the potential role of CBD as an alternative to opioids for pain management and addiction treatment.

As we look ahead, we remain optimistic about the possibilities of CBD and look forward to future developments in this exciting and rapidly evolving field. We hope you will continue to follow us as we continue to monitor these developments and continue to provide you with the most up-to-date and accurate information on CBD and opioids.

In the meantime, we invite you to explore our collection of flavor-enriched CBD products , including our popular Watermelon, Berry Gelato, and Bubble Gum flavors, as well as our effects blends designed to promote better sleep quality and faster recovery. We are here to support you on your wellness journey and look forward to helping you achieve your health and wellness goals.

Clearly, the road to understanding and effectively tackling the opioid epidemic is long and complex. But with continued advances in research and technology, and with the help of promising alternatives like CBD, we have reason to be hopeful. We are on the cusp of a new era in pain management and addiction treatment, and we look forward to the opportunities ahead.

In the meantime, it is important that we remain committed to education and awareness around opioids and CBD. We must continue to advocate for policy and regulatory changes that facilitate access to safe and effective treatments such as CBD. And we must continue to listen to and learn from patient experiences, which give us valuable insights into the challenges and opportunities of pain management and addiction treatment.

It is our hope that this article has made a useful contribution to this important discussion. We are grateful for your interest and involvement, and we look forward to working with you to create a better future for all affected by the opioid epidemic. Thank you for reading, and we hope you'll continue to follow us as we continue to explore these important issues.

Frequently Asked Questions

What is CBD?

CBD, or cannabidiol, is a naturally occurring compound in the cannabis plant. It is a non-psychoactive component, meaning it does not cause a "high" like THC.

How does CBD work for pain management?

CBD works by interacting with the endocannabinoid system in the body, which is involved in a wide variety of bodily functions, including pain. CBD can help reduce pain by modulating the activity of this system.

Can CBD Help Treat Opioid Addiction?

Recent research suggests that CBD may help treat opioid addiction by reducing drug craving and drug-related behaviors. In addition, CBD may help reduce the symptoms of opioid withdrawal.

What Are the Risks of Opioids?

Opioids have a high risk of abuse and dependence, and can lead to opioid use disorder. They can also lead to serious health problems, including overdose and death.

Is CBD legal?

The legal status of CBD varies worldwide. In the Netherlands, CBD is legal as long as the THC content is below 0.05%.

What are the possible side effects of CBD?

While CBD is generally well tolerated, some people may experience side effects such as dry mouth, fatigue, or changes in appetite or weight. It is always recommended to talk to a healthcare professional before starting to use CBD.

What is the difference between CBD and THC?

CBD and THC are both cannabinoids found in the cannabis plant, but they have different effects. THC is the psychoactive component of cannabis that causes a "high", while CBD is non-psychoactive and does not cause a high. In addition, CBD is often used for its potential therapeutic benefits, including pain relief and reduction of anxiety and depression.

How can I use CBD?

CBD can be used in a variety of ways, depending on your preference and the specific condition you want to treat. It can be taken as an oil or tincture, in capsule form, as an edible product, or it can be inhaled through vaping. It can also be applied topically in the form of creams or lotions for pain relief.

Are there different types of CBD products?

Yes, there are several types of CBD products available, including full-spectrum CBD, broad-spectrum CBD, and CBD isolate. Full-spectrum CBD contains all cannabinoids naturally occurring in the cannabis plant, including THC. Broad-spectrum CBD contains several cannabinoids, but no THC. CBD isolate contains only CBD.

Can I use CBD if I already use opioids?

If you're already using opioids, it's important to talk to your healthcare provider before you start using CBD. While there is some evidence that CBD and opioids may work synergistically to reduce pain, there may also be interactions between CBD and opioids that can affect your health.

What is the future of CBD in pain management and addiction treatment?

Given current trends and research findings, it is likely that CBD will play an increasingly important role in pain management and addiction treatment in the future. CBD's potential to treat opioid addiction and reduce pain without the risk of abuse and dependence makes it a promising alternative to opioids.